Abstract
A Virological Perspective on Cancer
Highlights
Lineberger Comprehensive Cancer Center and Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
Most cancer-associated infectious agents are oncogenic viruses that are linked to a multitude of different human cancers
My foray into the world of tumor virology began as a graduate student studying simian virus 40 (SV40) large T antigen, the viral oncoprotein whose function led scientists to discover the cellular tumor suppressor, p53
Summary
Most cancer-associated infectious agents are oncogenic viruses that are linked to a multitude of different human cancers. The field of tumor virology encompasses the study of all known oncogenic viruses. Identification of the intricate relationship between viruses and cancer was a landmark discovery that laid the foundation for our understanding of the concepts of modern cancer biology.
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