Abstract
* Abbreviations: ECG = : electrocardiogram • SIDS = : sudden infant death syndrome The article by Schwartz et al1 published in the New England Journal of Medicine reports on electrocardiographic (ECG) measurements made over a period of 18 years on infants on the 3rd day of life. It identifies those infants previously studied who died suddenly and unexpectedly and were diagnosed as having died of sudden infant death syndrome (SIDS), and compares their ECGs with those of the survivors. The idea that SIDS may be related to dysrhythmic events, the predisposing factor being an abnormally long QT interval, is one that at least merits attention. However, there are problems with any investigation whose basis relies on measurement of the QT interval as the authors admit. These problems include the possibility of including U waves in the measurement, the validity of using standard formula to calculate the QTc, and how one should deal with the variation of the QT interval with variation in heart …
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