Abstract

Silver nanoparticles stabilized by a well-known antibacterial surfactantbenzyldimethyl[3-(myristoylamino)propyl]ammonium chloride(Myramistin®) were produced for the first time by borohydride reduction of silver chloride sol in water.Stable aqueous dispersions of silver nanoparticles without evident precipitationfor several months could be obtained. In vitro bactericidal tests showed thatMyramistin® capped silver NPs exhibited notable activity against six differentmicroorganisms—gram-positive and gram-negative bacteria, yeasts and fungi.The activity was up to 20 times higher (against E. coli) compared toMyramistin® at the same concentrations and on average 2 times higher if compared with citrate-stabilizedNPs.

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