A Versatile Electrochemical Sensor Polyaniline−Polypyrrole Co-Polymer for the Ultra-Sensitive Quercetin Detection

Abstract

Quercetin has been shown to enhance inflammation, blood pressure, and blood sugar control. It may also have brain-protective, anti-allergy, and anticancer effects. In this work, a chemical oxidative polymerization approach is employed to synthesis of PANI-PPy copolymer for electrochemical biosensing of quercetin molecule. Unique, sustainable, low-cost, and simple to use, a synthesis of PANI-pPY copolymer has been achieved. The prepared PANI-PPy copolymer characterized with different technique like XRD, FT-IR, Raman, XPS, FESEM with EDAX and HR-TEM for identifying crystalline nature, functional group band gap, chemical composition, and morphology respectively. The surface morphology of the synthesized copolymers were in homogenous sphere like architecture. Synthesized copolymer is modified on glassy carbon electrode (GCE) to senses the biomolecule (Quercetin) by electrochemical method. PANI-PPy copolymer will greatly enhance the electrocatalytic oxidation of Quercetin (QR). The detection limit and quantification limit have been worked out to be 11.2 and 37.34 µM µA-1, respectively at neutral pH. All of the findings suggest that the PANI-PPy modified GCE is more sensitive to the oxidation of Quercetin. Eventually, the synthesized PANI-PPy hybrid may be used in catalysis research in addition to analytical laboratories due to its advantageous properties of enhanced catalytic activity and electrochemical sensitivity.