Abstract

Maturity-Onset Diabetes of the Young (MODY) is a group of monogenic autosomal dominant forms of diabetes, characterized by early-onset of hyperglycemia, and typically the presence of a family history of diabetes in more than one generation. These features are also present in Type 1 and Type 2 Diabetes Mellitus, which frequently leads to misdiagnosis. There are various MODY subtypes, caused by mutations in 14 known genes, which share a primary defect in insulin secretion.

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