Abstract
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Highlights
Over the last months and weeks of the pandemic of the Coronavirus Disease 2019 (COVID-19) (January-May 2020) caused by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there has been a significant hope for the development of vaccines against this emerging coronavirus
The structural proteins of SARS-CoV-2 include envelope (E), membrane (M), nucleocapsid (N), and spike (S) protein, which are being investigated as target antigens for vaccine development [10]
In this context, neutralizing antibodies were mainly reported to be directed against the S protein of the earlier zoonotic CoVs as it is the major structural protein can be targeted for the development of a vaccine against the SARS-CoV-2
Summary
Over the last months and weeks of the pandemic of the Coronavirus Disease 2019 (COVID-19) (January-May 2020) caused by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there has been a significant hope for the development of vaccines against this emerging coronavirus. Every aspect of SARS-CoV-2, its structural and non-structural proteins, genetic material, or the disease pathogenesis, are being explored for devising effective vaccines. A thorough understanding of the antigenic structures of SARS-CoV-2 is necessary for the development of vaccine [10].
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