Abstract
Uracil nitroso amine based colorimetric chemosensor for Cu2+ions from a 100% aqueous environment.
Highlights
Due to its redox-active nature, copper serves as an essential co-factor for a variety of metalloenzymes in living organisms such as cytochrome c oxidase, lysyl oxidase, copper-zinc superoxide dismutase and tyrosinase, which have a significant role in the enzymatic defense against oxygen toxicity.[7,8,9]
The absorption and color changes caused by the mixture of Cu2+ with the other metal ions was similar to that caused by Cu2+ alone (Fig. S5), which indicates that the other metal ions did not interfere with the binding of the chemosensor UNA-1 with Cu2+
The instantaneous color change of the solid silica gel in aqueous solution clearly inferred the practical application of UNA-1 for the qualitative detection of Cu2+ in aqueous medium
Summary
The third-most abundant transition element in the body, plays an important role in various physiological processes such as hemoglobin biosynthesis, bone development, dopamine production, nerve function regulation, gene expression, and the functional and structural enhancement of proteins.[1,2,3,4,5,6] Due to its redox-active nature, copper serves as an essential co-factor for a variety of metalloenzymes in living organisms such as cytochrome c oxidase, lysyl oxidase, copper-zinc superoxide dismutase and tyrosinase, which have a significant role in the enzymatic defense against oxygen toxicity.[7,8,9] at high concentration, its redox properties turn into biologically hazardous materials because of its ability to generate reactive species, which create problems in the cellular metabolism.[8,9] Apart from the biological and environmental importance, other advantages are that copper is relatively abundant, of low cost, and possess good malleability, electrical conductivity, thermal conductivity, chemical stability as well as germicidal efficiency. The observed color change clearly suggested that the sensor was quite sensitive up to a concentration of 5 х 10-5 M for the detection of Cu2+ ions. Upon addition of 5 equivalents of different cations (50 μL, 1 х 10-2 M, in water) to a 5 х 10-5 M solution of UNA-1 in CH3OH:H2O (10:90, v/v), only the Cu2+ ions was able to perturb the absorption spectrum of UNA-1 effectively.
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