Abstract
A very high impedance (10 12 ω at D.C.) amplifier has been designed and constructed for use with ultramicroelectrodes in neurophysiological investigations. The amplifier was designed to have exactly unity gain and to neutralize the interelectrode capacity of the input tube without the use of an external feedback capacitor to neutralize the grid to ground capacity of the microelectrode. Response is flat from D.C. to 700 kc., and a voltage step function applied to the input through 10 MΩ produces an output response with a time constant less than 3μ see. Grid current of the low noise input tube, Z729, is adjustable through zero.
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