Abstract

Myocardial Perfusion Imaging (MPI) is a non-invasive modality with proven diagnostic and prognostic utility in coronary artery disease. We present a case of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) where MPI findings were vastly different from Transthoracic Echocardiogram (TTE) and Cardiac Magnetic Resonance Imaging (CMR). A 78-year-old gentleman presented with atypical chest pain to rule out ischemic heart disease. He underwent MPI scan, revealing a medium-sized fixed perfusion defect of moderate intensity in the inferior segments.

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