Abstract
Summary 1.A case with roentgenologic evidence and clinical course of regional enteritis of at least nine (and possibly 11) years' duration was presented. Autopsy revealed diffuse adenocarcinoma involving segments of the small intestine, as well as the cecum, the ascending colon, and distant metastases. No typical histologic evidence of regional enteritis could be identified, although nonspecific inflammation was diffusely present. The only suggestive histologic item was the finding of pyloric type glands in a section of the ileum. 2.This case would be unique even if it were interpreted as an adenocarcinoma from the start. Reasons are adduced militating against such an assumption. 3.It is postulated that adenocarcinoma supervened on the basis of a burned out regional enteritis of long standing. 4.Only 1 case of carcinoma complicating regional enteritis was previously reported.
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