Abstract

Melanosis refers to abnormal or excessive deposition of melanin pigment in the cells and/or tissue, which can be seen in any organ but commonly in skin and oral mucosa. Melanosis of the urinary bladder is an extremely rare benign condition and only a handful of cases been reported in the English literature before. In this article, we report a new case of urinary melanosis, describe the differential diagnostic features from pseudomelanosis and offer clues for correct diagnosis. We also provide comprehensive review of the literature on the subject.

Highlights

  • Melanosis refers to abnormal/excessive deposits of melanin in the cells and/or tissue

  • Melanosis of the urinary bladder is a very rare benign condition and only 6 cases have been reported in English literature far [1,2,3,4]

  • The case was diagnosed as urinary melanosis

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Summary

Introduction

Melanosis refers to abnormal/excessive deposits of melanin in the cells and/or tissue. This condition can be seen in any organ but more frequently in the skin and oral mucosa. The patient is a 77 year-old African-American woman with medical history of urinary incontinence, large volume leakage, and severe urgency with leakage. She has been using diapers for the past two years. Clusters of punctuate dark spots were observed on the right lateral aspect of the bladder floor. The patient had no previous cystoscopy examination or any other pigmented lesions on the skin or mucosal surfaces

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