A unified approach to characterize and conserve adaptive and neutral genetic diversity in subdivided populations

Abstract

As extinction of local domestic breeds and of isolated subpopulations of wild species continues, and the resources available for conservation programs are limited, prioritizing subpopulations for conservation is of high importance to halt the erosion of genetic diversity observed in endangered species. Current approaches usually only take neutral genetic diversity into account. However, adaptation of subpopulations to different environments also contributes to the diversity found in the species. This paper introduces two notions of adaptive variation. The adaptive diversity in a trait is the excess of variance found in genotypic values relative to the variance that would have been expected in the absence of selection. The adaptivity coverage of a set of subpopulations quantifies how well the subpopulations could adapt to a large range of environments within a limited time span. Additionally, genome-based notions of neutral diversities were obtained that correspond to well known pedigree-based definitions. The values of subpopulations for conservation of adaptivity coverage were compared with their conservation values for adaptive diversity and neutral diversities using simulated data. Conservation values for adaptive diversity and neutral diversities were only slightly correlated, but the values for conservation of adaptivity coverage showed a reasonable correlation with both kinds if the time span was chosen appropriately. Hence, maintaining adaptivity coverage is a promising approach to prioritize subpopulations for conservation decisions.