Abstract
This is a report on three cases with massive bleeding into the digestive tract. In all cases, blood was found coming from the biliary tract via the biliary canaliculi. The hemorrhage was due to inflammatory bleeding in the Glisson's capsule caused by acute interstitial hepatitis. All patients were complicated with gallstone-like symptoms, urinary abnormal findings due to acute nephritis and impairment of the liver functions besides massive melena. They were all cured by administration of tetracycline. The author has found out that acute interstitial hepatitis could be one of the causes of massive melena.
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