Abstract
The field of microfluidics, small-scale tests from nanoscale to microscale, has grown dramatically over the past two decades as evidenced by greater than 30,000 papers published over the last 10 years on the topic [Web of Knowledge search using ‘microfluidic’ terms October 2011]. Microfluidic platforms, also known as lab-on-a-chip (LOC), include a set of miniaturized integrated unit operations that are touted to lead to fast, easy, precise control in biological and chemical systems. LOCs include the development of point-of-care (POC) medical diagnostic devices with the advantages of increased sensitivity, lower sample volumes, lower reagent volumes, low energy, low cost, low labor need, and less likelihood of human error (Xiao & Young, 2011). Due to these advantages, LOCs have substantial potential to be widely utilized in medicine for analytical and diagnostic assays, biosensors, and drug delivery.
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