Abstract
This article introduces a novel model that studies the major factors jeopardizing tuberculosis (TB) control programme in China. A previously developed two-strain TB model is augmented with a class of individuals not registered under the TB control programme. The paper investigates the basic reproduction number and proves the global stability of the disease-free equilibrium. The presence of three endemic equilibria is established in the model. With the help of numerical simulations, a comparative study has been performed to test the validity of the model presented here to the real data available from the Ministry of Health of the People's Republic of China. Sensitivity and elasticity analysis give the key parameters that would govern successful TB control in China.
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