A translocation in cattle and its association to polymorphisms in red cell antigens, transferrins and carbonic anhydrases.

Abstract

Investigations of the cattle karyotypes in the progeny groups of sires, heterozygous for a translocation of centric fusion type and back-crossed to normal dams, showed a deficient number of heterozygotes. As the ratio in the calves was approximately 1: 1 the deficiency in the total back-cross progeny, significant on the 95 per cent level, might have been due to selection against sexually mature females heterozygous for the translocation. Linkage of an order giving 10% crossing-over between the translocation and each of 10 loci controlling blood group antigens, transferrins and carbonic anhydrases could be excluded. Also linkage of an order giving 20% crossing-over could be excluded for the loci of the FV, SU, B and C blood groups, the transferrins and the carbonic anhydrases.