Abstract
BackgroundTo investigate the long-latency activities common to all sensory modalities, electroencephalographic responses to auditory (1000 Hz pure tone), tactile (electrical stimulation to the index finger), visual (simple figure of a star), and noxious (intra-epidermal electrical stimulation to the dorsum of the hand) stimuli were recorded from 27 scalp electrodes in 14 healthy volunteers.ResultsResults of source modeling showed multimodal activations in the anterior part of the cingulate cortex (ACC) and hippocampal region (Hip). The activity in the ACC was biphasic. In all sensory modalities, the first component of ACC activity peaked 30–56 ms later than the peak of the major modality-specific activity, the second component of ACC activity peaked 117–145 ms later than the peak of the first component, and the activity in Hip peaked 43–77 ms later than the second component of ACC activity.ConclusionThe temporal sequence of activations through modality-specific and multimodal pathways was similar among all sensory modalities.
Highlights
To investigate the long-latency activities common to all sensory modalities, electroencephalographic responses to auditory (1000 Hz pure tone), tactile, visual, and noxious stimuli were recorded from 27 scalp electrodes in 14 healthy volunteers
Following tactile stimulation, 'early' activations are elicited in area 3b, area 1 and the posterior parietal cortex in this order with a delay of 3–4 ms between each step, and a long-lasting 'late' activity is evoked in the secondary somatosensory area
There is a large and growing number of studies on multimodal interaction using electroencephalography (EEG) and MEG [813] as well as multimodal activation and interaction using functional magnetic resonance imaging [14,15,16,17], it is unclear whether or not the timing of the transition from unimodal to multimodal cortical activations is different among modalities
Summary
To investigate the long-latency activities common to all sensory modalities, electroencephalographic responses to auditory (1000 Hz pure tone), tactile (electrical stimulation to the index finger), visual (simple figure of a star), and noxious (intra-epidermal electrical stimulation to the dorsum of the hand) stimuli were recorded from 27 scalp electrodes in 14 healthy volunteers. We chose a simple manipulation of the ISI to extract more effectively the non-specific activities, to obtain a clearer result and to enable us to estimate more reliably and the location of the activity. Another reason for this choice is that the activities obtained by manipulating the ISI may be associated with orienting attention and later processes reflected by the non-specific N1 and P3a/P3b
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
