A tissue engineering dynamic culture instrument to provide cyclic dynamic mechanical stimulation

Abstract

The dynamic training of tissue engineering, which improves the training effect by providing mechanical stimulation for the engineering tissue, are getting more and more attention. Studies have shown that mechanical stimulation of cyclical changes simulate the physiological environment of human body more than continuous mechanical stimulation, which is more advantageous to the growth and differentiation of engineering tissues. However, the existing tissue engineering dynamic culture instrument or bioreactor usually uses constant mechanical stimulation to provide training environment for the engineering tissues. In order to improve the training effect by using the cyclic mechanical stimulation, the authors developed this tissue engineering culture instrument. The cultivation instrument achieves its core functions through a single-chip control system and provides an adjustable periodic mechanical stimulation. Key words: Tissue culture techniques; Tissue engineering; Patents; Dynamic culture; Cyclic mechanical stimulation