Abstract
Cats of heterogeneous stock and in good health were given daily oral doses of 92, 187, or 264 mg amaranth/kg/day for a time period extending from 0–22 days before the onset of gestation to Days 61–62 of gestation (mean gestation period = 65 days). The pregnancies were timed by having controlled copulation of females that were in an estrous state which occurred spontaneously or was stimulated by gonadotropin treatment. Cesarean section was performed on Day 61 or 62 of gestation. Maternal values including body weight gain, number of corpora lutea, and incidences of pregnancy, abortion, and nonpregnancy showed no amaranth-related adverse effect. There was no evidence of embryotoxicity as evaluated from the data on total implants, ratio of corpora lutea to total implants, dead fetuses, deciduomas, live fetuses, 24-hr viability of the live fetuses in an incubator, mean live fetal weight, sex ratio of live fetuses, and fetal anomalies.
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