Abstract
This work investigates the preparation of 1,7-dioxaspiro [5.5]undecane derivatives via the application of the template compound 2,8-bis(bromomethyl)-1,7-dioxaspiro [5.5]undecane and a series of catalysed carbonyl-ene reactions introducing aromatic and non-aromatic linkers to the heterocyclic system, providing an alternative approach to various marine toxin fragments.
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