A technique for global assessment of respiratory muscle performance at different lung volumes

Abstract

A system for noninvasive assessment of an all-inclusive function of respiratory muscles at different lung volumes is presented. The apparatus was based on the interrupter technique and facilitated simultaneous measurements of mouth pressure and airflow rate during dynamic or quasi-static manoeuvres. In this study, mouth pressure values were continuously acquired during and after interruption of a forced inspiratory or expiratory manoeuvre for as long as the subject could sustain an elevated mouth pressure against the obstructed opening. These measurements provided information on both muscle strength and power. A total of 420 forced maximal inspiratory and expiratory manoeuvres performed by six healthy subjects were monitored at different lung volumes. The pattern of maximal pressure-time curves was consistent for the same subject regardless of lung volume. Similar values of maximal mouth pressure can be generated by healthy subjects by using either a flange-style mouthpiece or facial mask. For both methods mouth pressure shows a significant ( p < 0.05) second order dependency on lung volume for both inspiration and expiration. The standard deviation of measurements from a single subject about a second order curve is of the order of 5-15%. The findings of interchangeability between methods of measurement may be useful in allegedly non-compliant patients. Keywords: mouth pressure, respiratory muscle strength, respiratory muscle endurance, interrupter technique