Abstract
A technique utilizing microspheres for the evaluation of tubal patency and ovum transport function in the rabbit is described. After iv injection of human chorionic gonadotropin (HCG) uteri were exposed and a Geiger-Muller (G-M) tube was inserted so that the end was immediately proximal to the utero-tubal junction. A single 400-450 mcm microsphere was placed in the tubal ampulla on the side containing the G-M tube. The method was tested in 3 groups of animals: 1) controls treated with HCG alone 2) animals treated with progesterone and 3) animals ligated at the midampullar region. The method detected uterine entry of the microsphere or failure of transport in every instance. This system permits evaluation of various compounds for their effects on ovum transport rates in rabbits.
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