Abstract
after an anthelmintic treatment. This technique has been used widely for veterinary and medical purposes (Drudge and Lyons, 1977, American Journal of Veterinary Research 38: 1581-1585; Croll and Ghadirian, 1981, Tropical and Geographical Medicine 33: 241-248; Anderson and Schad, 1985, Transactions of the Royal Society of Tropical Medicine and Hygiene 79: 812-825; Bundy et al., 1985, Transactions of the Royal Society of Tropical Medicine and Hygiene 79: 232-237; Bundy et al., 1985, Transactions of the Royal Society of Tropical Medicine and Hygiene 79: 641-644), however, to our knowledge, it has not been documented for laboratory animals. It is our belief that this technique could be particularly useful to immunologists, epidemiologists, and ecologists working on intestinal helminths in laboratory animals. This experiment was designed to determine the rate of expulsion, after anthelmintic treatment, of adult Heligmosomoides polygyrus Dujardin, 1845, for use in nondestructive estimation of worm burden. The effects of sex of the host, number of adult worms, and dose of the drug on the expulsion rate were examined. The H. polygyrus strain was obtained from Dr. A. E. Keymer (Oxford University) and maintained in CD1 mice. This nematode has a direct
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