A tale of two studies: is there a reproducibility problem in the anaesthetic literature?

Abstract

AnaesthesiaEarly View Editorial A tale of two studies: is there a reproducibility problem in the anaesthetic literature? J. Gadsden, Corresponding Author J. Gadsden Professor [email protected] orcid.org/0000-0003-3971-3879 @@jeffgadsden Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA Correspondence to: J. Gadsden Email: [email protected]Search for more papers by this author J. Gadsden, Corresponding Author J. Gadsden Professor [email protected] orcid.org/0000-0003-3971-3879 @@jeffgadsden Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA Correspondence to: J. Gadsden Email: [email protected]Search for more papers by this author First published: 02 June 2023 https://doi.org/10.1111/anae.16056 Professor, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA This editorial accompanies an article by Albrecht et al., Anaesthesia 2023; 78: 315–9. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1Hussain N, Brummett CM, Brull R, Alghothani Y, Moran K, Sawyer T, Abdallah FW. Efficacy of perineural versus intravenous dexmedetomidine as a peripheral nerve block adjunct: a systematic review. Regional Anesthesia and Pain Medicine 2021; 46: 704– 12. 2Jung HS, Seo KH, Kang JH, Jeong J-Y, Kim Y-S, Han N-R. Optimal dose of perineural dexmedetomidine for interscalene brachial plexus block to control postoperative pain in patients undergoing arthroscopic shoulder surgery. Medicine 2018; 97: e0440. 3Sehmbi H, Brull R, Ceballos KR, et al. Perineural and intravenous dexamethasone and dexmedetomidine: network meta-analysis of adjunctive effects on supraclavicular brachial plexus block. Anaesthesia 2021; 76: 974– 90. 4Albrecht E, Vorobeichik L, Jacot-Guillarmod A, Fournier N, Abdallah FW. Dexamethasone is superior to dexmedetomidine as a perineural adjunct for supraclavicular brachial plexus block. Anesthesia and Analgesia 2019; 128: 543– 54. 5Abdallah FW, Dwyer T, Chan VWS, et al. IV and perineural dexmedetomidine similarly prolong the duration of analgesia after interscalene brachial plexus block. Anesthesiology 2016; 124: 683– 95. 6Kang RA, Jeong JS, Yoo JC, et al. Improvement in postoperative pain control by combined use of intravenous dexamethasone with intravenous dexmedetomidine after interscalene brachial plexus block for arthroscopic shoulder surgery: a randomised controlled trial. European Journal of Anaesthesiology 2019; 36: 360– 8. 7Albrecht E, Capel D, Rossel JB, Wolmarans MR, Godenèche A, de Paulis D, Cabaton J. A randomised controlled trial of intravenous dexmedetomidine added to dexamethasone for arthroscopic rotator cuff repair and duration of interscalene block. Anaesthesia 2023; 78: 315– 9. 8Baker M. 1,500 scientists lift the lid on reproducibility. Nature 2016; 533: 452– 4. 9Lindner MD, Torralba KD, Khan NA. Scientific productivity: an exploratory study of metrics and incentives. PLoS One 2018; 13: e0195321. 10Youyou W, Yang Y, Uzzi B. A discipline-wide investigation of the replicability of psychology papers over the past two decades. Proceedings of the National Academy of Sciences 2023; 120: e2208863120. 11Serra-Garcia M, Gneezy U. Nonreplicable publications are cited more than replicable ones. Science Advances 2021; 7: eabd1705. 12Klein AA. What Anaesthesia is doing to combat scientific misconduct and investigate data fabrication and falsification. Anaesthesia 2017; 72: 3– 4. 13Vasilopoulos T, Wardhan R, Rashidi P, et al. Patient and procedural determinants of postoperative pain trajectories. Anesthesiology 2021; 134: 421– 34. 14Neuman MD, Feng R, Carson JL, et al. Spinal anesthesia or general anesthesia for hip surgery in older adults. New England Journal of Medicine 2021; 385: 2025– 35. 15Clarke M, Hopewell S, Chalmers L. Reports of clinical trials should begin and end with up-to-date systematic reviews of other relevant evidence: a status report. Journal of the Royal Society of Medicine 2007; 100: 187– 90. 16Avidan MS, Ioannidis JPA, Mashour GA. Independent discussion sections for improving inferential reproducibility in published research. British Journal of Anaesthesia 2019; 122: 413– 20. 17Ioannidis JPA, Tatsioni A, Karassa FB. Published articles should not be dead and buried: introducing research updates. European Journal of Clinical Investigation 2010; 40: 767– 9. Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation