Abstract
After sudden outbreak of covid-19 pandemic, to overcome this chaotic situation many drug therapies have been used which includes Chloroquine, Hydroxychloroquine (Antimalarial), Lopinavir and Ritonavir (antiviral), Nafamostat (Sirin protease inhibitor), Famotidine (Antihistamines), Nitazoxanide (Anti-infective), Evermectin (Anti-parasitic), Corticosteroids, Tocilizumab & Sarilumab (Inflammatory cytokine), Fluvoxamine(Anti-depressants), but due to prominent effect of 2-DG it has been extensively used against SARS-CoV-2. It is a glucose molecule which was approved for the emergency treatment in covid-19 pandemic against SARS-CoV-2 by inhibiting glycolysis-The energetic cycle. It shows more highlighting effect with combinational approach. This drug was sanctioned by Drug Controller General of India (DCGI) and has been developed by Institute of medicine and Allied Sciences (INMAS), a lab of Defence Research and Development Organization (DRDO), together with Dr Reddy’s Laboratories (DRL), Hyderabad.
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