A systematic review on the WHO Global Priority Pathogens (GPP) List reported in animals, products, and by-products in Colombia

Abstract

Background: The World Health Organization (WHO) published the Global Priority Pathogens (GPP) List for the Research and Development of Effective Antibiotics in 2017, a catalog of bacteria to be prioritized in the global fight against bacterial antibiotic resistance. Objective: To collect and app raise the scientific evidence on bacteria listed as GPP in animals and their products and by-products in Colombia, identifying knowledge gaps and providing finding-based recommendations. Materials and Methods: The review was carried out according to PRISMA guidelines. Only original articles published in peer35 reviewed journals were considered. Results: Twenty-one articles, published between 2001 and 2021, met the inclusion criteria. The geographical areas of study were the provinces of Antioquia, Cundinamarca —including Bogotá C.D., and Santander and Tolima. The main bacteria from the WHO´s list reported were fluoroquinolone-resistant Salmonella, methicillin-resistant and vancomycin-intermediate and resistant Staphylococcus aureus, and carbapenem-resistant ESBL-producing Enterobacteriaceae. The sources were feces, facilities, equipment, feed, animal drinking water, bed chip, tissues, and carcasses, related to broilers and laying hens, cattle, and pigs. Conclusions: Results obtained herein afford important advances in the knowledge of the phenomenon and its dynamic in Colombia. Nevertheless, much remains to be researched in the country, including standardized methods for the microbiological identification in veterinary medicine, as well as the evaluation of the antibiotic susceptibility patrons in bacteria in accordance with what is done in humans, among other aspects.