Abstract

Stroke is considered to be the fourth leading cause of death and became the fifth leading cause of disability. The global stroke fact sheet released in 2022 reveals that the risk of stroke has increased by 50% over the last 17 years and at present 1 in 4 people is estimated to have a stroke in their lifetime. According to the centre for disease control and prevention, over 2.7 million people die from Ischemic stroke globally. High cholesterol may increase the risk of stroke by boosting the risk of vascular disease, which is a risk factor of stroke. The relationship between the lipids and stroke is complex, on investigation, the total cholesterol level, LDL-C, the total cholesterol to HDL-C ratio and non HDL-C are significantly associated with the increased risk of ischemic stroke. Statins are effective in preventing the vascular diseases and are widely recommended for the secondary prevention and management of ischemic stroke by significantly decreasing the cardiovascular risk and improving functional performance to improve clinical outcome in preventing the recurrence of ischemic stroke.

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