Abstract

Alzheimer's disease (AD) is the most frequent cause of dementia, however, and it is caused by a number of different disorders. With regard to the elderly population all over the world, Alzheimer's disease is the seventh largest cause of mortality, disability, and reliance. Depression, social isolation, inactivity, alcohol, smoking, obesity, diabetes, high blood pressure, and age are all variables that can increase the likelihood of getting dementia. Other risk factors include social isolation, depression, and smoking. A diagnosis of Alzheimer's disease at an earlier stage may improve the odds of receiving care and therapy. Medical professionals often diagnose AD based on a limited number of symptoms. On the other hand, it is now possible to identify and categorize Alzheimer's disease (AD) because of technological advancements such as artificial intelligence (AI). However, to identify the current AI-enabled approaches, we must conduct an investigation into the state of the art. This breakthrough in diagnosis methodologies will enable the development of the Clinical Decision Support System (CDSS), capable of automatically diagnosing Alzheimer's disease (AD) without human expertise. In this publication, we conduct a systematic review of sixty research articles previously reviewed by other researchers. The systematic review sheds light on the synthesis of new knowledge and ideas. This study discusses the current approaches for machine learning, deep learning methods, ensemble models, transfer learning, and methods used for early Alzheimer's disease diagnosis. This paper provides answers to a large number of research issues and synthesizes fresh information that is helpful to the reader on many elements of AI-enabled approaches for Alzheimer's disease diagnosis. In addition, it has the potential to stimulate additional research into more effective methods of computer-based intelligent identification of Alzheimer's disease.

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