A Systematic Review of Clinical Decision Support Systems in Alzheimer’s Disease Domain

Sherimon P.C,Vinu Sherimon,Rahul Nair,Renchi Mathew,Preethii S.P

doi:10.3991/ijoe.v17i08.23643

Abstract

Dementia is one of the major public health issues faced by the world. Alzheimer’s disease (AD) is the most common form of dementia targeting old age groups around the world. It is a neurodegenerative condition with memory loss as its early symptom. Unfortunately, there is no cure for this disease currently. So various research in the medical and technical fields are being conducted to help people with Alzheimer’s. Many studies focus on early diagnosis of Alzheimer’s disease using clinical decision support system (CDSS) so that the progression of the disease can be slowed down to a great extent. In this context, we have undertaken a research to design and implement an ontology based Clinical decision support system for Alzheimer’s disease in Sultanate of Oman. A semantic knowledgebase (ontology) will be the core component of our Clinical decision support system. The objective of this research paper is two-fold (a) review the medical aspects of Alzheimer’s disease, and (b) review the available clinical decision support system based on ontology, robotics, and mobile applications in Alzheimer domain. Research articles published during 2011- 2020 in PubMed, Google scholar, Elsevier, SpringerLink and IEEE journals were reviewed. We found that there is various clinical decision support system which can aid physicians in suggesting diagnosis, and treatment of Alzheimer’s disease.

Highlights

Dementia is a syndrome associated with persistent deterioration in brain function
Alzheimer’s is the most common cause of dementia affecting millions of people around the world.Alzheimer’s disease (AD) is a neurodegenerative disease usually presented in older people who are 65 years of age and more
Alzheimer’s disease (AD), the most common type of dementia worldwide. It is a neurodegenerative condition usually presented in the older people at the age of 65 years and above and is the sixth leading cause of death in the United States [2]

Summary

Introduction

Dementia is a syndrome associated with persistent deterioration in brain function. It can affect memory, thinking, and other mental abilities [1]. Alzheimer’s is the most common cause of dementia affecting millions of people around the world.AD is a neurodegenerative disease usually presented in older people who are 65 years of age and more. It causes neuronal cell death resulting in cerebral atrophy and widening of third ventricle of brain[2].

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