A Systematic Review Comparing Fusion Rates and Cage Subsidence in ACDF by Cage Alone vs Cage and Plate in Multilevel Cervical Disc Prolapse

Abstract

Abstract Background Anterior cervical discectomy and interbody fusion (ACDF) has become the standard procedure for treating degenerative cervical disc disease. Multiple techniques and modalities of fixation are used in ACDF, each with its merits and demerits. Aim of the Work The objective of this study is to compare the outcome of anterior cervical discectomy and fusion by cage alone versus surgical fusion by cage and plate in terms of morbidity, mortality, fusion rates, cage subsidence and quality of life estimates in treatment of multilevel cervical disc prolapse. Patients and Methods Our search strategy identified a total of 235 citations. Search was done for studies conducted or published within 2010 – 2022. After removal of 58 duplicate studies, eligibility criteria was applied to the titles of 177 articles with the exclusion of non-appropriate study design. This yielded 21 studies that underwent full text analysis of which 13 did not meet the inclusion criteria for having only single level ACDF or short follow up period. Results Our study included 8 observational studies (6 retroscpective and 2 prospective) comparing multilevel ACDF with cage alone vs cage and plate regarding fusion rate and cage subsidence, the results showed that while the cage plate group had lower rate of cage subsidence, there was no significant difference in the rate of fusion. Conclusion Our study included 8 observational studies (6 retroscpective and 2 prospective) comparing multilevel ACDF with cage alone vs cage and plate regarding fusion rate and cage subsidence, the results showed that while the cage plate group had lower rate of cage subsidence, there was no significant difference in the rate of fusion.