A Systematic Review and Meta-analysis of the Use of Simmering Pus and Growing Flesh Method to Promote Postoperative Wound Healing in Anorectal Diseases

Abstract

Objective: To systematically review the clinical efficacy and progress of Chinese medicine's external treatment method guided by the theory of simmering pus and growing flesh to promote postoperative wound repair in anorectology. Methods: Clinical randomized controlled trials (RCTs) of simmering pus and growing flesh method to promote postoperative wound healing in anorectology were collected by a computer search of China Knowledge Network (CNKI), Wanfang (WANGFANG DATA), VIP (VIP), China Biomedical Literature Database (CBM) and other means, and the screening of articles and the extraction of article data were performed according to the inclusion and exclusion criteria.Meta-analysis of the extracted data was also performed using Stata14 software, to compare the overall efficacy, mean wound healing time, and other clinical observations of patients with postoperative wounds in anorectal medicine by the external Chinese medicine method of simmering pus and growing flesh with the non-simmering pus and growing flesh method. Results: The final 12 publications were included, with a total of 931 study participants, and the Meta results showed that the TCM external treatment of simmering pus and growing flesh method helped to shorten the mean wound healing time [WMD=-3.791 , 95% CI (-4.629 , 2.952), P<0.05], improve the 14-day wound healing rate [WMD=9.341 , 95% CI (6.951 , 11.731), P<0.05], and improved postoperative wound recovery efficiency in anal diseases [RR=3.099, 95% CI (1.898, 5.060), P<0.05].Conclusion: The simmering pus and growing flesh method helps to improve the average healing time and wound healing rate of postoperative wounds in anal diseases, thus improving the efficiency of postoperative wound repair in anal diseases.