Abstract
Background: Escherichia coli O157: H7 is shiga toxinproducing Escherichia coli which is recognized as an important cause of diarrhea, hemorrhagic colitis and hemolytic-uremic syndrome worldwide. The aim of this systematic review and meta-analysis is to assess the burden of Escherichia coli O157:H7 and its antibiotic resistance pattern in different foods in Ethiopia. Methods: The literature search was conducted to identify all published articles reporting the proportion and antimicrobial susceptibility pattern of shiga toxin producing Escherichia coli O157:H7 in foods. From all screened articles, 21 studies were eligible for i¬A‚Ânal systematic review and meta-analysis. Statistical analysis was done by using STATA14 software. Results: The pooled proportion of Escherichia coli O157:H7 is 0.05 (95% CI, 0.04 to 0.07%). Moreover, Shiga toxin-producing Escherichia coli strains were found to be highly resistant to Chloramphenicol, Tetracycline, Erythromycin and Streptomycin, with a pooled resistance ratio of 79.72, 63.44, 52.65, and 50.77%, respectively. On the other hand, comparably low levels of resistance ratio were noted to Nitrofurantoin 7.54% and Norfloxacin 9.72%. Conclusion: The overall burden of Escherichia coli O157:H7 is low. However, it indicates the probability of food contamination by Escherichia coli O157:H7. And, E. coli O157:H7 showed resistance to Chloramphenicol, Tetracycline, Erythromycin and Streptomycin.
Highlights
Shiga-toxin producing Escherichia coli (STEC) is recognized as an important foodborne zoonotic pathogen
More than 400 different serotypes of STEC have been isolated, O157:H7 is the serotype that has been most studied since it has been commonly associated with the development of severe human illness [2]
One of major pathogenic microorganisms that frequently have been associated with food borne disease is Escherichia coli O157:H7
Summary
Shiga-toxin producing Escherichia coli (STEC) is recognized as an important foodborne zoonotic pathogen. Recent epidemiological studies have revealed other STEC called non-O157 sero-types, to be highly associated with human disease [3]. Ruminants such as cattle, sheep, goats, and deer are considered significant reservoirs of STEC, while other animals have been found infected [4,5,6]. The aim of this systematic review and meta-analysis is to assess the burden of Escherichia coli O157:H7 and its antibiotic resistance pattern in different foods in Ethiopia. Shiga toxin-producing Escherichia coli strains were found to be highly resistant to Chloramphenicol, Tetracycline, Erythromycin and Streptomycin, with a pooled resistance ratio of 79.72, 63.44, 52.65, and 50.77%, respectively. E. coli O157:H7 showed resistance to Chloramphenicol, Tetracycline, Erythromycin and Streptomycin
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
