A systematic review and meta-analysis examining the benefits of quantitative exercise intervention on effective bowel preparation prior to colonoscopy.

Abstract

This study systematically evaluated and analyzed the efficacy of quantitative exercise intervention on colonoscopy intestinal preparation. A systematic search was performed using the Cochrane Library, the JBI evidence-based database, Embase, Web of Science, CINAHL, Medline, CNKI, the China Biomedical Literature Database (CBM), and the Wanfang database to identify literature relating to the efficacy of exercise intervention on bowel preparation for colonoscopy. Randomized controlled trials (RCTs) and clinical controlled trials (CCTs) published from the establishment of the database to July 2021 were included. After screening the literatures, relevant data was extracted and evaluated for quality. The RevMan 5.3 software was used for meta-analysis. A total of 8 studies with 1,486 patients, including 747 in the intervention group and 739 in the control group, were included in this meta-analysis. The results of 4 studies showed that the use of quantitative exercise intervention programs did significantly improve the quality of the patient's bowel preparations [mean difference (MD) =2.15, 95% confidence interval (CI): 0.04 to 4.26; P=0.046]. The results of 6 studies demonstrated that the use of quantitative exercise intervention programs can effectively improve the patient's bowel preparation adequacy rate [relative risk (RR) =1.25, 95% CI: 1.05 to 1.49; P=0.012]. Meta-analysis of 5 studies showed that the use of quantitative exercise intervention programs can reduce the incidence of nausea in patients (RR =0.52; 95% CI: 0.37 to 0.74; P=0.000). Analysis of 4 studies revealed that quantitative exercise intervention can reduce the incidence of vomiting in patients (RR =0.36; 95% CI: 0.23 to 0.56; P=0.000). Furthermore, evaluation of 4 studies demonstrated that quantitative exercise intervention reduced the incidence of abdominal pain in patients (RR =0.50; 95% CI: 0.28 to 0.89; P=0.019), and reduced the incidence of abdominal distension (RR =0.60; 95% CI: 0.36 to 0.99; P=0.047). Quantitative exercise intervention can effectively improve the quality of intestinal preparation before colonoscopy and reduce the incidence of adverse reactions.