A Systematic Analysis of Literary Case Reports of Protein S Deficiency Implicated in Pathogenesis of Arterial Thrombosis

Pratyay Hasan

doi:10.19080/jocct.2017.06.555685

Abstract

A Systematic Analysis of Literary Case Reports of Protein S Deficiency Implicated in Pathogenesis of Arterial Thrombosis

Highlights

IntroductionDeficiency of protein S is long known to cause venous thrombosis but not arterial thrombosis
Introduction and backgroundProtein S is a vitamin K dependent natural anticoagulant
Further larger studies should be undertaken to determine the true contribution of deficient protein S level in pathogenesis of arterial thrombosis

Summary

Introduction

Deficiency of protein S is long known to cause venous thrombosis but not arterial thrombosis. The anticoagulant property of Protein S has been discovered by Walker et al.[3] Hereditary deficiency of protein S has been long known for causing venous thrombosis but the effect of the deficiency in pathogenesis of arterial thrombosis is much less acknowledged [4,5]. It is because, thrombophilia is usually associated with venous, rather than arterial thrombosis. Carod-Artal et al [10] found that prothrombotic

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Discussion

Conclusion