A survey study on the relationship between helminthes infection and other microorganism infection

Abstract

Parasitic helminthes infections take place mostly in regions where exposure to other pathogens is as well prevalent. A parasitic worm infestation may encourage infection with another microbe. There are many hypotheses and evidence for how this is done First, helminths naturally encourage a T-helper cell type 2 (Th2) immune response, relating cytokines for example interleukin IL-4, IL-5 and IL-13. seacond in cooperation Th2 and Treg responses have been proposed to decline the generation of protective Th1 or Th17 immunity against bacterial or viral pathogens. Third helminth-modified intestinal metabolism promotes susceptibility to microbe coinfection. This search summarizes our recent understanding in what way the host’s immune response to infection with various kinds of parasitic worm affect susceptibility to predisposition to infection with further microbes.