Abstract
The odontogenic tumors are classified into three groups: Epithelial, mesenchymal, and mixed. The dentinoma, a pure mesenchymal tumor, is composed of connective tissue in which denticles or islands of irregularly formed dentine are present. The odontogenic mixed tumors consist of epithelial and mesodermal elements which are in combination in various proportions and arrangements. Three types are recognized: Soft, soft and calcified, and calcified. The soft type has been differentiated from the solid adamantoblastoma. There is evidence of the inductive influences of one tissue on another in the odontogenic mixed tumors. It is noted that epithelium in these tumors seems to stimulate dentine formation, but that the presence of epithelium is not necessary for the production of dentine. Also, dentine is formed in the presence of epithelial cells not differentiated into ameloblasts. Neoplastic adamantine tissue and enamel-forming ameloblasts have been distinguished. The presence of these two types accounts, in part, for the formation of the soft and calcified odontogenic mixed tumors.
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