Abstract
The explosion of a land mine which avulses a leg or the perforation of the leg by a shell fragment does not result in only a local wound. Although tissue destruction is primarily a local wound, the loss of blood and the absorption of bacterial toxins are, at least, two concomitant injuries which constitute a wound of the entire organism. Since both the leg and the entire organism are injured, it is not surprising that both respond to the injury in the fight for survival. This response to injury includes a response of every organ, every system, and, presumably, every cell in the body. The changes in plasma electrolyte concentrations are not in themselves but are reflections of dynamic changes within the myriad of cells of the many organs, the chief of which is the wound. These changes are believed to represent, in part, the injury and resultant cell
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