Abstract
Little is reported about primary cardiac osteosarcoma from mitral valve. We report a surgical case of primary cardiac osteosarcoma arising from mitral valve. The patient was a 54-year-old woman with congestive heart failure caused by mitral regurgitation due to a tumor (30 × 20 mm) from the posterior leaflet. We performed complete resection of the tumor combined with the mitral valve and replaced it to a mechanical valve. Histopathological examination showed evidence of complete excision of cardiac osteosarcoma. Sixteen months after the initial surgery, the mechanical valve has a trouble with its opening of leaflets due to local recurrence in the mitral annulus, and 2nd mitral valve replacement following tumor excision was performed. Eighteen months after the 2nd surgery, the patient finally died by recurrence as well as invasion of osteosarcoma from mitral annulus to left ventricular myocardium. We discussed about the management and treatments of primary cardiac osteosarcoma in this case.
Highlights
Primary osteosarcoma of the heart is rare
We report a surgical case of primary cardiac osteosarcoma arising from mitral valve
We accomplished complete surgical resection and mitral valve replacement (MVR) against primary cardiac osteosarcoma arising from mitral posterior leaflet
Summary
In the patients with primary cardiac sarcoma, complete surgical resection of the tumor is recognized as the most effective and essential treatment to obtain longer survival period for the patients [1]. In this case, we accomplished complete surgical resection and mitral valve replacement (MVR) against primary cardiac osteosarcoma arising from mitral posterior leaflet. Despite the complete resection of the primary tumor, the local recurrence caused the prosthetic valve dysfunction leading to severe congestive heart failure. We discussed about the management and treatments of primary cardiac osteosarcoma from mitral valve
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