Abstract
Objective: To evaluate the prevalence and clinic-etiologic profile of thrombocytopenia in pregnancy:
 Materials and Methods: The present hospital based observational study was conducted in the Department of Obstetrics and Gynecology, Patna Medical College and Hospital, Patna, Bihar from July 2016 to January 2017. A detailed obstetrics history was obtained and maternal high risk factors like preeclampsia, eclampsia, DIC, HELLP syndromes etc were noted. Medical history like anemia, malaria, dengue, liver disorder, current or previous bleeding problems, family history of bleeding & transfusion history were noted. Clinical findings suggestive of thrombocytopenia like petechiae, ecchymoses etc. were noted.
 Results: Out of total 74 patients, Gestational thrombocytopenia was the most common etiological factor with 41.9% cases followed by 35.1% for hypertensive disorders including HELLP syndrome followed by 6.8% for Malaria and dengue. The most common hemorrhagic presentation was petechiae, ecchymosis & purpura in 33.8% cases. Among the thrombocytopenic pregnant women in our study, 60.8% had mild thrombocytopenia, 24.3% had moderate thrombocytopenia and 14.9% had severe thrombocytopenia
 Conclusion: The study demonstrated that thrombocytopenia is a frequent finding in pregnancy. It has many potential causes but gestational thrombocytopenia (GT) predominates. Degree of thrombocytopenia was mild to moderate.
 Keywords: Pregnancy, Thrombocytopenia, Petechiae, Ecchymosis
Highlights
Thrombocytopenia during pregnancy has become a cause for unnecessary, often invasive, additional testing and cesarean deliveries
Due to hemodilution secondary to expansion of plasma volume, platelet count in normal pregnancies may be decreased by ~10%; most of the decrease in platelet count occurs during the third trimester of pregnancy[1,2,3], the absolute platelet count remains within normal reference range in most patients.[4,5]
Thrombocytopenia can be classified as mild, moderate or severe.[6]
Summary
Thrombocytopenia during pregnancy has become a cause for unnecessary, often invasive, additional testing and cesarean deliveries. The evaluation and treatment of this condition can be expensive and distressing to the patient and can result in an adverse outcome. Thrombocytopenia is suspected when a patient’s platelet count is
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