A STUDY TO EVALUATE MATERNAL AND FETAL OUTCOME IN TERM PREGNANCY WITH MECONIUM STAINED AMNIOTIC FLUID: A PROSPECTIVE OBSERVATIONAL STUDY AT A TERTIARY CARE CENTRE IN INDIA

Abstract

Background: Globally, 7-22% of all live births are complicated by meconium stained amniotic uid (MSAF). MSAF is considered a predictor of adverse fetal outcome, and meconium aspiration syndrome, a major cause of perinatal morbidity and mortality. This study aimed to nd out the incidence of MSAF and to nd a clinical correlation of neonatal outcome with amnioinfusion and mode of delivery among the study groups. Methods: A prospective observational study was conducted at Sassoon General Hospital, Pune, India from October 2017 to March 2019. 206 patients who fullled the inclusion criteria were studied. Subgroups of with/without amnioinfusion were analyzed in terms of mode of delivery and neonatal outcome. Results: The incidence of MSAF in term pregnancies was found to be 9.13 %. Patients were divided into 2 study groups: thick MSAF and thin MSAF. 76.2% of patients were managed with amnioinfusion. A signicant reduction in the number of cesarean sections observed among patients with thick MSAF. A signicant improvement in APGAR score was observed in newborns with amnioinfusion for thick MSAF. There was a decrease in neonatal intensive care unit stay, neonatal morbidity and mortality. Conclusion: Taking the risks of MSAF into consideration, a trial of labour should be given where continuous electronic fetal monitoring and emergency cesarean section facilities are available. Amnioinfusion decreased the rate of emergency cesarean section and improved the APGAR score in patients with thick MSAF.