Abstract

Background: To compare the RNFL measurements using the conventional Time Domain Optical Coherence Tomography (TD-OCT) 'Stratus' and the Spectral Domain Optical Coherence Tomography (SD OCT) 'RTVue' in healthy participants and glaucoma patients. ThisMethods: prospective cross-sectional study included 50 eyes in each of the two study groups as, healthy eyes and eyes of established glaucoma patients. Peripapillary RNFL thickness was measured by both machines in random order by the same operator on the same day with pupils uniformly dilated to over 5.0 mm. Three separate fast RNFL Scans were acquired with Stratus OCT, from which the most reliable scan was chosen for comparison. For RTVue, “RNFL3.45” scan protocol was used, which consists of four sets of 1024 “A-scans” along a 3.45 mm-diameter circle centered on the optic disc. There was a signicant difference in RNFL measurements between the two methods ,which was maximum in the superiorResults: quadrant and minimum in the nasal quadrant in both the groups In both the groups, RTVue RNFL measurements are thicker as. Conclusion: compared to that of Stratus with maximum quadrant mean RNFL measurement in the inferior quadrant and minimum in the nasal quadrant. Maximum difference in RNFL measurement between the two machines was at superior quadrant in both the groups.

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