Abstract

Hemophilia was thought to be a uniform entity for several centuries. The discovery that the coagulation defect in the blood of one hemophilic could be normalized by infusion of blood from another hemophilic in 1940 led to finding that there were two types of hemophilia: hemophilia A, due to deficiency of coagulation factor Ⅷ and Hemophilia B, caused by the reduction of coagulation factor Ⅸ. Hemophilia was divided into three different degrees of severity: severe, moderate and mild. In severe hemophilia, the plasma content of coagulation factor activity is less than 1% of normal, compared with 1 to 4% in moderate hemophilia and 5 to 40% in mild cases.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call