Abstract
Purpose: To study the corneal endothelium by specular microscopy in middle aged patientswith cataract. Methods: this is observational cross-sectional retrospective clinical study. Itincluded 500 eyes of 500 patents (244 females and 256 males) with cataract whose ages werebetween 40 and 60 (mean, 51.99 ± 7.32) that accepted to participate in this study in Sohagophthalmic investigation center from the period of September 2017 to November 2018. Noncontact Topcon specular microscopy (model SP-1S, Japan) was performed in the studied eyes.Endothelial cell density (ECD), coefficient of variation (CV) in cell size, hexagonality of cells(HEX), and number of cells (N) were measured. Results: ECD readings ranges from 2017-3931with a mean of 2835.29 and SD of 476.01. The median of COV is 36 and the range liesbetween 23-91. The mean of HEX is 50.61 with SD of 9.85 while the median is 52. Number ofcorneal cells in the study group ranges from 97-457 cells with a mean of 158.39 cells and SD of55.86, while the median is 145 cells. The results of the present study revealed that WKH PHDQRIendothelial cell density is 2835.29 ± 476.01 cell/mm2, coefficient of variation in cell size is 37.78± 9.60 %, hexagonality of cells is 50.16 ± 9.85 % and number of cell is 158.39 ± 55. 86 cells.Conclusion: Specular microscopy can provide a non invasive morphologic analysis of thecorneal endothelial cell layer from subjects enrolled in clinical trials.
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