A Study on the Relationship between Iron Reserves and the Intensity of Coronary Artery Stenosisin Angiography Candidates

Khalil Mahmoodi

doi:10.31031/cojnh.2018.02.000528

Abstract

Various risk factors including blood iron may create coronary artery diseases and lead to myocardial infarction. There are controversies with regard to the impact of blood iron on myocardial infarction. Therefore, the aim of this paper was to investigate the relationship between iron reserves and the intensity of coronary artery stenos is among angiographic candidates in Zanjan, Iran. This was a cross sectional study. Samples were consisted of patients who were hospitalized for diagnostic coronary angiography in hospitals in an urban area of Iran. A convenient sampling method was used to recruit samples via interviews and laboratory examinations for FBS, iron, TIBC, ferritin, creatinine serum, CBC, cholesterol, HDL and LDL. The samples were divided into control and intervention groups. After coronary angiography, the intervention group was evaluated by four different methods including the extent score, stenos is score, vessel score and Duke CAN Index. The samples were consisted of 89 men (60.1%) and 59 women (39.9%). The levels of ferritin (p=0.003) and iron (p=0.002), and transferrin saturation percent (p=0.002) showed significant differences between males and females (p=0.004)

Highlights

Coronary artery disease (CAD) is the most rampant disease that leads to mortality and morbidity
This study showed that the intensity of coronary artery stenosis had a relationship with the body iron reserves
The intensity of coronary artery stenosis was related to the body iron reserves

Summary

Introduction

Coronary artery disease (CAD) is the most rampant disease that leads to mortality and morbidity. The prevention of CAD and reduction of the patients’ mortality rate are the concerns of the healthcare system across the world Achieving such a goal requires improving our understanding of risk factors related to them [3, 4, 5]. Coronary risk factors are consisted of hereditary and nonadjustable ones such as age, gender, family background and adjustable ones including obesity, smoking, blood pressure and diabetes mellitus [6]. Another risk factor for CAD is the body iron reserves [7]. Sullivan (1981) for the first time proposed that the body iron reserves can probably have a positive relationship with CAD [12]

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Conclusion