Abstract
Syzygium guineense is one of the most widespread African tree species about more than 30 m tall with edible fruits. Aim: Present review is an attempt to provide utmost information based on ethnomedicinal, phytochemical and pharmacological aspects of S. guineense. Method: We searched PubMed, Medline, EMBASE, CINAHL, Psyc INFO and Web of Science databases to identify studies reporting phytochemical and harmacological aspects of S. guineense. We made a systematic review of all the activities that have already been done on S. guineense Results: A total of one hundred and seventy-eight articles were downloaded, sixty-six studies were included. Primary constituent’s chlorophyll, lipids, sugars and proteins while secondary compounds include alkaloids, terpenoids, polyphenols, alkaloids, saponins, steroids, cardiac glycosides, flavonoids, tannins and coumarin. Research also has shown that S. guineense powder contains minerals such as Calcium, Potassium, Rubidium, Phosphorus, Strontium, Sulphur, Zirconium, Manganese, Iron, Titanium. Anti-inflammatory, analgesic, antioxidant, anti-diabetic, anti-cancer, antimycobacterial, anti-Sickle, antispasmodic, immunological and mollucidal activities were found. Conclusion: This systematic review dealt with the phytochemical of S. guineense and its pharmacological activities. It emerges that S. guineense contains a variety of primary (amino acids, proteins, sugars) and secondary (polyphenols, flavonoids, saponins, tannins, alkaloids, terpernoids and many others) metabolites which contain several pharma-cological activities which act at dif erent levels against oxidative stress, sickle cell disease, bacterial and viral infections
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