Abstract
A Study on the Origin of Bovine Rotavirus Strains Detected from the Children of the Nasu District, Tochigi, Japan
Highlights
Rotavirus (RV), is an important viral pathogen causing Acute Gastroenteritis (AGE) in humans
In 37 cases in VP6, NSP4 gene-based Reverse Transcribed-Polymerase Chain Reaction (RT-PCR) 24 samples were positive and the genotypes were determined as G1P[8] in 5 samples, G3P[8] in 5 samples, G9P[8] in 3 samples, and G6P[9] in 2 samples
G6P[9] have been detected from more than 3 cats of Mie Prefecture. These findings suggest that human G6 RVs which had occurred by reassortment between human and bovine RVs are distributed worldwide, despite low prevalence
Summary
Rotavirus (RV), is an important viral pathogen causing Acute Gastroenteritis (AGE) in humans. As most of infants have received the rotavirus vaccine rotavirus infections among infants and young children has since decreased significantly in developed countries [1]. The vaccine prevents an estimated 40,000 to 50,000 hospitalizations among U.S infants and young children [2]. RV infects humans but non-human monkeys and bovine, pigs, horses, dogs, cats, rats and chicken. Serious gastrointestinal infection of Rotavirus (RV) is usually prevalent during winter months and often seen in infants and young children. Studies on genotypes of prevalent rotavirus strains are quite important for preventing infection, developing vaccines, and its evaluation. G6 human rotavirus is quite rare, it is the major type among rotaviruses from cattle. In this study we investigated the characteristics and origin of bovine RV strains from the children of the Nasu district, Tochigi, Japan
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