A study on the effectiveness of Guggulu based Karanja Ksharasutra in comparison with Apamarga Ksharasutra in the management of Shalyaja Nadivrana with special reference to Pilonidal Sinus

Abstract

Shalyaja Nadivrana is an Agantuja variety of Vrana. Nidana Panchaka and treatment is extensively described in Sushruta Samhita - Nidhana and Chikitsa Sthana. Presence of Shalya in the tract is an obstacle to its healing. Management of Nadivrana includes Ksharasutra therapy. The pilonidal sinus is an acquired sinus that develops in young, hirsute men, usually in the intergluteal cleft caused by the intrusion of hair into the skin, causing an abscess and gradually forming a sinus. The study was conducted on 40 randomly assigned patients at SJAUM Hospital, Bengaluru by dividing them into 2 groups - Group A and Group B. These groups were treated with Guggulu-based Karanja Ksharasutra and Apamarga Ksharasutra respectively. Assessment of pain, discharge, LOT, tenderness, and induration in Group A showed 91.67%, 91.3%, 99.9%, 85.19%, 95% and 75.6% improvement and Group B showed 87.5%, 86.96%, 100%, 78.6% and 97.37% improvement respectively. Group A’s overall result was 89.5% and Group B’s overall result was 89.9%. The mean UCT of Group A was 8.3 days/cm and Group B was 7.9 cm/day with p -value <0.05 which is significant. The study showed that the trial drug was as good as the control drug in the management of Shalyaja Nadi Vrana.