A Study on the Correlation of Various Factors in Patients With Severe Traumatic Brain Injuries.

Abstract

Traumatic brain injury (TBI), ranging from minor impacts to severe cases, affects temporal and frontal brain areas, contributing to mortality and disability worldwide. The Glasgow Coma Scale (GCS) evaluates consciousness levels, aiding in prioritizing emergency care, while the Disability Rating Score (DRS) assesses overall function, particularly in severe cases, with greater sensitivity than GCS for clinical changes in TBI patients. To correlate various factors with each other in patients presented with severe TBIs. The retrospective study analyzed data from patients with severe TBIsadmitted to the hospital from February 2023to April 2024. Patients' demographic and clinical data, including GCSand DRSscores, were collected. Statistical analysis, including logistic regression, assessed mortality predictors. The study revealed significant correlations (p<0.05) between age and marital status (p=0.002) and surgery (p=0.003). Surgery also correlated significantly with the mechanism of injury (p<0.001). Furthermore, a negative correlation was found between GCS after 24 hours and change in GCS (p<0.001), while a positive correlation existed between DRS after 24 hoursand DRS on the 14th day (p<0.001). These findings highlight the complex interplay between demographic factors, medical interventions, and clinical outcomes in TBI patients. The study found that older individuals, particularly those involved in road traffic accidents, had poorer recovery outcomes and higher rates of surgery, with a strong correlation between changes in GCSand DRSscores.