Abstract

Objective To evaluate whether small endoscopic sphincterotomy (EST) plus balloon dilation (EPBD) can replace endoscopic sphincterotomy (EST) alone for patients with common bile duct (CBD) stones.Methods From May 2008 to April 2011,462 patients with CBD stones were randomly divided into two groups.The success rate of complete stone removal after the first session,the rate of using mechanical lithotripsy (ML),the short-term complications,the procedure time and fluo roscopy time were compared between the two groups.Results Overall ductal clearance did not differ between the two groups (96.5% vs 93.5%,P>0.05).The complication rates at 24 hours were 6.9% for the small EST plus EPBD group and 11.7% for the EST group (P>0.05).However,the rate of complete stone removal after the first session using small EST plus EPBD was significantly higher than EST alone (86.2% vs 70.4%,P<0.05).ML was required significantly more often in the EST group when compared with the small EST plus EPBD group (34.8% vs 12.1%,P<0.05).The total procedure time and total fluoroscopy time in the small EST plus EPBD group were significantly shorter than the EST group [(38.6±15.5) min vs (47.1±20.2) min,P<0.05 and (17.3± 7.0) min vs (26.5±10.8) min,P<0.05].Conclusions Compared with EST,small EST plus EPBD was safe and more efficacious for bile duct stones.In the future,small EST plus EPBD probably can replace EST to be the first treatment of choice for bile duct stones. Key words: Cholelithiasis; Sphincterotomy, endoscopic; Balloon dilation

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