Abstract
Sinusitis is common, but rarely localized to the sphenoid sinus. The sphenoid sinus has an intimate anatomical relationship with the cavernous sinus, internal carotid artery, and many cranial nerves (II, III, IV, V1-V2, VI). Therefore, the spread of infection or inflammation beyond the sphenoid sinus to these structures may result in serious or even fatal intracranial or orbital complications.
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